FRI biomarkers

Imaging Biomarkers

FRI has the unique capability of producing highly clinical relevant patient specific biomarkers, presenting 3D visualization of the patient’s airway and lung geometry, regional airway resistance and aerosol deposition patterns.

The effectiveness of these biomarkers in facilitating correct diagnoses and monitoring patient outcomes has been validated in over 20 clinical trials, conducted with a total of 750 patients, performed in collaboration with various academic and medical research centers. These trials confirmed the higher sensitivity of FRI, through its use of biomarkers, compared with existing standard diagnostic tests such as spirometry.

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The imaging biomarkers measure:

  • Internal airflow distribution: A measurement of the inhaled air delivered to the individual lung lobes
  • Lung volume: A measurement of the lung content in liters
  • Lobe volume: A measurement of the lobe content in liters
  • Airway volume: A measurement of the content of the central and distal airways in liters
  • Airway resistance: A computation of the resistance and impendance experienced by the central and distal airways
  • Lobar perfusion: A measurement of the blood vessel density in the individual lobes
  • Aerosol deposition: A computation of the regional deposition patterns of inhaled drugs
  • Airway wall volume: A measurement of the volume of the airway wall of the central and distal airways

Table: Overview of primary FRI parameters for different lung diseases. For all lung diseases, all other parameters can be used as secondary FRI parameters.

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2550 Kontich

Belgium

BE 0877 160 706

Tel: +32/(0)3 450 87 20

Fax: +32/(0)3 450 87 29

info@fluidda.com

MiRC, LDA

Medical Imaging Research Corporation
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1700-239 Lisbon
Portugal

MiRC, LDA

Medical Imaging Research Corporation
Avenida da igreja 42, 6th floor
1700-239 Lisbon
Portugal

FLUIDDA, Inc

228 East 45th Street
9th Floor - Suite 9E
New York, NY 10017
United States

FLUIDDA, Inc

228 East 45th Street
9th Floor - Suite 9E
New York, NY 10017
United States

FLUIDDA India

Medical Imaging pvt ltd
A-95/96, DGP Nagar -2, Ambad
Nashik 422010
India

FLUIDDA India

Medical Imaging pvt ltd
A-95/96, DGP Nagar -2, Ambad
Nashik 422010
India

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