1 Image Acquisition

To obtain this data about a patient, only two low dose HRCT scans taken during total inspiration (TLC) and normal expiration (FRC) are needed.

1 Image Acquisition

To obtain this data about a patient, only two low dose HRCT scans taken during total inspiration (TLC) and normal expiration (FRC) are needed.

2 Structure Segmentation

From the HRCT scans, the patient-specific airway and lung structures are segmented and 3D reconstructed. Several structural patient-specific parameters, such as lung and airway volumes, emphysema or air trapping can be obtained at this stage, at a lobar level. These 3D reconstructed structures from the CT scans form the basis for further functional analysis using CFD.

2 Structure Segmentation

From the HRCT scans, the patient-specific airway and lung structures are segmented and 3D reconstructed. Several structural patient-specific parameters, such as lung and airway volumes, emphysema or air trapping can be obtained at this stage, at a lobar level. These 3D reconstructed structures from the CT scans form the basis for further functional analysis using CFD.

3 Flow simulation

FRI technology combines CT images with an advanced Computational Fluid Dynamics (CFD) tool to provide both structural and functional parameters. CFD analyses the motion of fluids and their interaction with surfaces. This advanced technology in aerospace engineering can be applied to healthcare, accurately describing the patient’s “geometry” (lungs, arteries, heart, etc.) and “boundary” conditions (blood flow velocity, airflow pressures, etc.). This results in a detailed, functional imaging, allowing to provide patient-specific parameters such as airway resistance and aerosol deposition characteristics.

3 Flow simulation

FRI technology combines CT images with an advanced Computational Fluid Dynamics (CFD) tool to provide both structural and functional parameters. CFD analyses the motion of fluids and their interaction with surfaces. This advanced technology in aerospace engineering can be applied to healthcare, accurately describing the patient’s “geometry” (lungs, arteries, heart, etc.) and “boundary” conditions (blood flow velocity, airflow pressures, etc.). This results in a detailed, functional imaging, allowing to provide patient-specific parameters such as airway resistance and aerosol deposition characteristics.