New publication on FRI: Assessment of small pulmonary blood vessels in COVID-19 patients using HRCT
Mounting evidence supports the role of pulmonary hemodynamic alterations in the pathogenesis of COVID-19.
Building upon previous work, automated HRCT measures of small blood vessel volume and pulmonary vascular density were developed. Scans from 103 COVID-19 patients and 108 healthy volunteers were analyzed and their results compared, with comparisons made on both lobar and global levels.
COVID-19 patients showed significant reduction in BV5 (pulmonary blood volume contained in blood vessels of <5 mm2) expressed as BV5/(total pulmonary blood volume) (p<0.0001), and significant increases in BV5_10 and BV 10 (pulmonary blood volumes contained in vessels between 5 and 10 mm2 and above 10 mm2, respectively) (p<0.0001). These changes were consistent across lobes.
COVID, COVID-19, Publication