Tag: COPD | Fluidda

Tag Archives: COPD

Differences found in lung deposition of extrafine vs non-extrafine triple therapies in patients with COPD using FRI.

Posted on 17 September 2019 by Huub Koets • 0 Comments

This study will be presented at ERS 2019 at a thematic poster session on Monday September 30 between 12.50 pm and 2.40 pm.

Functional Respiratory Imaging evaluated lung deposition patterns of extrafine ICS/LABA/LAMA with a pressurized metered dose inhaler (pMDI) and non-extrafine ICS/LABA/LAMA with a dry powder inhaler (DPI), in patients with stable COPD and moderate to very severe airflow obstruction.

FRI data indicated a higher peripheral lung (small airways) deposition with extrafine triple therapy than with non-extrafine. This may be attributed to the lower Mass Median Aerodynamic Diameter (MMAD) of the extrafine formulation.

Jan de Backer, CEO and founder of Fluidda, speaks about the partnership with Materialise at the ATS conference.

Posted on 11 June 2019 by Huub Koets • 0 Comments

De Backer states: “We are very excited and proud to enter into this new phase of partnership with Materialise. We share the vision that the medical field, and particularly respiratory healthcare imaging needs to evolve towards personalized, precision medicine through a value-based healthcare approach. We are confident that advanced imaging techniques, such as our Functional… Continue Reading

Jan de Backer, CEO and founder of Fluidda, explains the purpose of the FIGHT-project at the ATS conference.

Posted on 3 June 2019 by Huub Koets • 0 Comments

FIGHT is a non-profit charity project which has been established together with FLUIDDA, focusing on research of the lung health of Californian firefighters. The key purpose of the charity is to examine lung diseases rooting from wildfire smoke exposure, investigate how these diseases can be detected earlier on, and determine how treatment protocols can be… Continue Reading

FRI can speed up development of novel treatments for COPD and other lung diseases.

Posted on 27 May 2019 by Huub Koets • 0 Comments

At IRDD, May 30 in New York, Dr. De Backer will discuss the clinical relevance of understanding regional lung structure and function in the development of novel treatments for lung diseases. Functional Respiratory Imaging (FRI) and Artificial Intelligence (AI) can greatly facilitate the development of novel inhaled treatments for COPD and other lung diseases through… Continue Reading

FRI technology used in PhD thesis on hyperinflation and COPD exacerbations

Posted on 18 April 2019 by Huub Koets • 0 Comments

Last October, Wouter van Geffen, pulmonologist at the Medical Center Leeuwarden, The Netherlands, was awarded his PhD degree for this thesis titled: Hyperinflation and COPD exacerbations. In chapter four of this dissertation, the heterogeneity of acute COPD exacebations was investigated using Functional Respiratory Imaging (FRI). COPD exacerbations are a major burden to patients and yet… Continue Reading

Machine learning algorithms utilizing functional respiratory imaging may predict COPD exacerbations

Posted on 23 November 2018 by Tom Van Rossom • 0 Comments

Acad Radiol. 2018 Nov 23. pii: S1076-6332(18)30487-2. Authors Lanclus M, Clukers J, Van Holsbeke C, Vos W, Leemans G, Holbrechts B, Barboza K, De Backer W, De Backer J. Read more Continue Reading

FRI shows clinically meaningful benefits of Bevespi in COPD

Posted on 31 August 2018 by Jan De Backer • 0 Comments

We are happy to announce that a few days ago the positive results of AstraZeneca’s Bevespi (LABA/LAMA), compared to placebo have been published in the International Journal of COPD. The study shows how FRI confirmed the strong, homogeneous effect of the innovative co-suspension bronchodilator compared to placebo, as seen in earlier studies. At the same… Continue Reading

A randomized study using FRI to characterize bronchodilator effects of glycopyrrolate formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD

Posted on 30 August 2018 by Tom Van Rossom • 0 Comments

Int J Chron Obstruct Pulmon Dis. 2018 Aug 30;13:2673-2684. Authors De Backer W, De Backer J, Vos W, Verlinden I, Van Holsbeke C, Clukers J, Hajian B, Siddiqui S, Jenkins M, Reisner C, Martin UJ. Read more Continue Reading

Functional respiratory imaging: heterogeneity of acute exacerbations of COPD

Posted on 22 June 2018 by Tom Van Rossom • 0 Comments

Int J Chron Obstruct Pulmon Dis. 2018; 13: 1783–1792. Authors van Geffen WH, Hajian B, Vos W, De Backer J, Cahn A, Usmani OS, Van Holsbeke C, Pistolesi M, Kerstjens HAM, De Backer W Read more Continue Reading

Changes in ventilation-perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling

Posted on 22 June 2018 by Tom Van Rossom • 0 Comments

Int J Chron Obstruct Pulmon Dis. 2018 Mar 6;13:833-842. Authors Bita Hajian, Jan De Backer, Wim Vos, Wouter H van Geffen, Paul De Winter, mar Usmani, Tony Cahn, Huib AM Kerstjens, Massimo Pistolesi, Wilfried De Backer Read more Continue Reading